Myocardial infarction occurs when heart muscle cells die as a consequence of oxygen deprivation. Occasionally this can happen when the oxygen-carrying capacity of the blood is reduced, and there is general hypoxaemia...
Chronic heart failure (CHF) is a life-threatening condition that is becoming more common in most countries due to improved treatments for acute coronary syndromes (Kushner 2009). In addition, with ageing of the population, the number of people at risk of developing CHF has also increased. Improving the management of CHF is a high and growing priority for cardiovascular health services...
Cardiovascular disease remains the leading cause of morbidity and mortality worldwide, and therefore strategies that aim to improve prevention in people without existing disease (primary prevention) are important for managing the overall burden of disease. This edition of The Cochrane Library adds to the evidence-base in this area with publication of two Cochrane Reviews on such preventive strategies: multiple risk factor interventions for primary prevention of coronary heart disease, and statins for the primary prevention of CVD...
In one of the press releases accompanying the publication of Issue 1, 2011 of The Cochrane Library we mistakenly stated the following: "However, there is less evidence that statins are beneficial for preventing heart problems in those who have no history of CVD. Given that low cholesterol has been shown to increase the risk of death from other causes, statins may do more harm than good in some patients" ...
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