The Cochrane Library is a collection of six databases that contain different types of high-quality, independent evidence to inform healthcare decision-making, and a seventh database that provides information about groups in The Cochrane Collaboration.
Dr David Tovey is the first Editor in Chief of The Cochrane Library (since 2009) and oversees the CDSR content.
Dr Tovey is based in the Cochrane Editorial Unit, along with Harriet MacLehose (Senior Editor) and Toby Lasserson (Senior Editor), Rachel Marshall (Editor), John Hilton (Editor), and Ruth Foxlee (Information Specialist). You can contact the Editor in Chief via email at editorial-unit@cochrane.org. Other contact details are available on the Cochrane Editorial Unit website.
John Wiley & Sons, Ltd. publishes The Cochrane Library. Deborah Pentesco-Gilbert, publisher, can be contacted at:
John Wiley & Sons, Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK. Email: dpentesc@wiley.com.
The Cochrane Database of Systematic Reviews (CDSR) is the leading resource for systematic reviews in health care.
The CDSR includes all Cochrane Reviews (and protocols) prepared by Cochrane Review Groups in The Cochrane Collaboration. Each Cochrane Review is a peer-reviewed systematic review that has been prepared and supervised by a Cochrane Review Group (editorial team) in The Cochrane Collaboration according to the Cochrane Handbook for Systematic Reviews of Interventions or Cochrane Handbook for Diagnostic Test Accuracy Reviews. Find out more about Cochrane Reviews and Protocols.
The 2011 Impact Factor for the CDSR was announced as 5.912. The CDSR is ranked in the Top Ten of the Journal Citation Reports® (JCR) "Medicine, General & Internal" category. Download a fact sheet for the 2011 CDSR Impact Factor here. For the 2010 CDSR Impact Factor click here or for the 2009 CDSR Impact Factor click here.
If you are interested in attending an Impact Factor Webinar, please contact Gavin Stewart gstewart@wiley.com +44 (0)1243 770 686.
The Cochrane Reviews in the CDSR are prepared by authors who register titles with one of the 53 Cochrane Review Groups. Each Cochrane Review Groups focuses on a specific topic area and is led by a Co-ordinating Editor(s) and an editorial team including a Managing Editor and Trials Search Co-ordinator. The Cochrane Review Groups provide authors with methodological and editorial support to prepare Cochrane Reviews, and manage the editorial process, including peer review.
| Cochrane Review Group | Co-ordinating Editor(s) | Contact |
|---|---|---|
| Acute Respiratory Infections | Prof Chris Del Mar, Anne GM Schilder |
Website | Details in 'About' database |
| Airways | Dr Chris Cates | Website | Details in 'About' database |
| Anaesthesia | Prof Anne Merete Møller, Prof Nathan Pace |
Website | Details in 'About' database |
| Back | Dr Claire Bombardier, Prof Maurits W van Tulder |
Website | Details in 'About' database |
| Bone, Joint and Muscle Trauma | Dr Helen HG Handoll | Website | Details in 'About' database |
| Breast Cancer | Dr Nicholas Wilcken | Website | Details in 'About' database |
| Childhood Cancer | Dr Leontien CM Kremer, Dr Elvira van Dalen | Website | Details in 'About' database |
| Colorectal Cancer | Prof Richard L Nelson, Peer Wille-Jørgensen |
Website | Details in 'About' database |
| Consumers and Communication | Dr Sophie Hill | Website | Details in 'About' database |
| Cystic Fibrosis and Genetic Disorders | Dr Alan R Smyth | Website | Details in 'About' database |
| Dementia and Cognitive Improvement | Dr Jenny McCleery, Dr Rupert McShane |
Website | Details in 'About' database |
| Depression, Anxiety and Neurosis | Dr Rachel Churchill | Website | Details in 'About' database |
| Developmental, Psychosocial and Learning Problems | Prof Geraldine Macdonald | Website | Details in 'About' database |
| Drugs and Alcohol | Dr Marina Davoli | Website | Details in 'About' database |
| Ear, Nose and Throat Disorders | Mr Martin J Burton | Website | Details in 'About' database |
| Effective Practice and Organisation of Care | Prof Jeremy Grimshaw | Website | Details in 'About' database |
| Epilepsy | Prof Anthony G Marson | Website | Details in 'About' database |
| Eyes and Vision | Mr Richard Wormald | Website | Details in 'About' database |
| Fertility Regulation | Prof Frans M Helmerhorst | Website | Details in 'About' database |
| Gyneacological Cancer | Dr Chris Williams, Dr Jo Morrison |
Website | Details in 'About' database |
| HIV/AIDS | Dr George W Rutherford, Dr Nandi Siegfried |
Website | Details in 'About' database |
| Haematological Malignancies | Prof Andreas Engert, Dr Nicole Skoetz |
Website | Details in 'About' database |
| Heart | Dr Juan-Pablo Casas, Prof Shah Ebrahim |
Website | Details in 'About' database |
| Hepato-Biliary | Dr Christian Gluud | Website | Details in 'About' database |
| Hypertension | Dr James M Wright | Website | Details in 'About' database |
| Incontinence | Prof Cathryn MA Glazener, Prof James MO N'Dow |
Website | Details in 'About' database |
| Infectious Diseases | Prof Paul Garner, Dr David Sinclair |
Website | Details in 'About' database |
| Inflammatory Bowel Disease and Functional Bowel Disorders | Dr Brian G Feagan | Website | Details in 'About' database |
| Injuries | Dr Pablo Perel, Prof Ian Roberts |
Website | Details in 'About' database |
| Lung Cancer | Dr Fergus MacBeth, Dr Sera Tort |
Website | Details in 'About' database |
| Menstrual Disorders and Subfertility | Prof Cindy Farquhar | Website | Details in 'About' database |
| Metabolic and Endocrine Disorders | Prof Bernd Richter | Website | Details in 'About' database |
| Methodology Review | Prof Mike J Clarke, Dr Andrew D Oxman |
Details in 'About' database |
| Movement Disorders | Prof Cristina Sampaio | Website | Details in 'About' database |
| Multiple Sclerosis and Rare Diseases of the Central Nervous System | Dr Graziella Filippini | Website | Details in 'About' database |
| Musculoskeletal | Prof Rachelle Buchbinder, Dr Peter Tugwell |
Website | Details in 'About' database |
| Neonatal | Dr Roger Soll | Website | Details in 'About' database |
| Neuromuscular Disease | Dr Michael PT Lunn, Dr Rosaline Quinlivan |
Website | Details in 'About' database |
| Occupational Safety and Health | Dr Jos Verbeek | Website | Details in 'About' database |
| Oral Health | Prof Jan E Clarkson, Prof Helen V Worthington |
Website | Details in 'About' database |
| Pain, Palliative and Supportive Care | Prof Christopher Eccleston | Website | Details in 'About' database |
| Peripheral Vascular Diseases | Dr Jackie Price, Prof Gerry Stansby |
Website | Details in 'About' database |
| Pregnancy and Childbirth | Prof Zarko Alfirevic, Prof James P Neilson |
Website | Details in 'About' database |
| Prostatic Diseases and Urologic Cancers | Dr Philipp Dahm, Prof Howard G Kynaston (Cardiff satellite), Prof Malcolm Mason (Cardiff satellite) |
Website | Details in 'About' database |
| Public Health | Prof Elizabeth Waters | Website | Details in 'About' database |
| Renal | Prof Jonathan C Craig, Dr Angela C Webster |
Website | Details in 'About' database |
| Schizophrenia | Prof Clive E Adams | Website | Details in 'About' database |
| Sexually Transmitted Infections | Dr Hernando G Gaitán | Website | Details in 'About' database |
| Skin | Prof Hywel C Williams | Website | Details in 'About' database |
| Stroke | Peter Langhorne | Website | Details in 'About' database |
| Tobacco Addiction | Dr Tim Lancaster | Website | Details in 'About' database |
| Upper Gastrointestinal and Pancreatic Diseases | Dr Grigorios I Leontiadis, Prof Paul Moayyedi |
Website | Details in 'About' database |
| Wounds | Prof Nicky A Cullum | Website | Details in 'About' database |
The Cochrane Library databases CDSR, Central & About are published monthly. DARE, CMR, HTA & EED are published quarterly with the DVDs, according to a regular schedule.
All Cochrane Reviews are published in the CDSR. The CDSR is published online monthly with quarterly DVDs. As outlined on the access page, access is free for many people in low-income and middle-income countries via a number of initiatives. This is in addition to general access options, including national licenses (eg such as in the United Kingdom) and subscriptions.
Authors of registered Cochrane Reviews should contact their Cochrane Review Group for support, information about editorial processes, and information about editorial deadlines.
Authors interested in preparing a Cochrane Review should contact the Cochrane Review Group that covers the area of interest for information about the registration process. Prospective authors should first browse the CDSR to identify whether the topic of interest is already covered by an ongoing protocol or review.
View “How to prepare a Cochrane Review” for further information, including author resources and training information.
| 1972 | Publication of Archie Cochrane's 'Effectiveness and Efficiency: random reflections on health services' , which drew attention to our collective ignorance about the effects of health care |
| 1974 | Identification of controlled trials in perinatal medicine begins in Cardiff, Wales, UK |
| 1979 | Archie Cochrane publishes an essay in which he suggests that "It is surely a great criticism of our profession that we have not organised a critical summary, by specialty or subspecialty, adapted periodically, of all relevant randomised controlled trials." He also designates obstetrics the least scientific medical specialty |
| 1985 | Publication of classified bibliography of 3500 reports of controlled trials in perinatal medicine published between 1940 and 1984 |
| 1989 to 1992 | Maintenance of systematic reviews of controlled trials of perinatal care in six-monthly disk issues of an electronic journal, The Oxford Database of Perinatal Trials (ODPT) |
| October 1992 | The first Cochrane Centre opened (in the UK) and the first Cochrane Review Groups were registered (Pregnancy and Childbirth Group, and the Subfertility Group) |
| April 1993 | Update Software reissues The Oxford Database of Perinatal Trials (ODPT) as a redesigned pilot electronic journal entitled The Cochrane Pregnancy and Childbirth Database (CCPC) |
| August 1993 | Formal launch of The Cochrane Collaboration at the 1st Cochrane Colloquium, in Oxford, UK |
| October 1994 | First public demonstration of the Cochrane Database of Systematic Reviews (CDSR), designed and published by Update Software |
| February 1995 | CDSR launched in London by the English Minister for Health |
| March 1996 | The Cochrane Library launched by Update Software as a quarterly publication on CD-ROM and disk, incorporating the Cochrane Database of Systematic Reviews (CDSR), Database of Abstracts of Reviews of Effectiveness, Cochrane Controlled Trials Register, and Cochrane Review Methodology Database |
| August 1996 | CDSR available on the World Wide Web |
| April 1997 | Electronic Comments and Criticisms System launched within the CDSR |
| January 2001 | One thousandth Cochrane Review published |
| April 2002 | The Cochrane Library made free at the point of use, under the HINARI programme |
| October 2002 | John Wiley and Sons Limited publish The Cochrane Library |
| October 2003 | Launch of La Cochrane Library Plus en español |
| June 2008 | First impact factor: 4.654 for 2007; ranked 14 out of 100 worldwide journals in the Medicine, General and Internal category |
| January 2009 | First Editor in Chief of The Cochrane Library, Dr David Tovey Number of published Cochrane Reviews and Protocols reaches 5676 in Issue 1, 2009 |
| January 2010 | CDSR moves to monthly publication |
| August 2011 | Cochrane Reviews have new online 'Look and Feel' |
| January 2012 | Cochrane CENTRAL moves to monthly publication |
| September 2012 | 'New Search' functionality released for global usage. |
Feedback on individual Cochrane Reviews is welcomed, and there is a dedicated process for this. Readers of a review or protocol can do this by clicking on the “submit comments” button, under ARTICLE TOOLS, on the right-hand side of the review.
As of April Issue4, 2013, the CDSR includes 7825 records: 5484 reviews; and 2341 protocols. APRIL Issue includes 35 new reviews, updated reviews include 43 with a new search and 9 with changed conclusions, 45 new protocols, with 8 updated protocols. There was also 2 withdrawn reviews, 12 withdrawn protocols. Totalling 201 withdrawls in CDSR.
The Database of Abstracts of Reviews of Effects (DARE) is the only database to contain abstracts of systematic reviews that have been quality-assessed. Each abstract includes a summary of the review together with a critical commentary about the overall quality.
DARE is a key resource for busy decision-makers and can be used for answering questions about the effects of specific interventions, whether such questions arise from practice or when making policy. DARE covers a broad range of health related interventions and thousands of abstracts of reviews in fields as diverse as diagnostic tests, public health, health promotion, pharmacology, surgery, psychology, and the organization and delivery of health care.
DARE complements the CDSR by quality-assessing and summarizing reviews that have not yet been carried out by The Cochrane Collaboration.
DARE is produced by the Centre for Reviews and Dissemination (CRD) at the University of York, UK.
The Cochrane Central Register of Controlled Trials (CENTRAL) includes details of published articles taken from bibliographic databases (notably MEDLINE and EMBASE), and other published and unpublished sources. CENTRAL records include the title of the article, information on where it was published (bibliographic details) and, in many cases, a summary of the article. They do not contain the full text of the article.
About three-fifths of the records in CENTRAL are taken from MEDLINE. Also, each Cochrane Review Group maintains and updates a collection of controlled trials relevant to its own area of interest, these are called ‘Specialized Registers’. Each Cochrane Review Group may also collect items that are not relevant to its own field of interest; these are known as ‘Handsearch Results’.
All Cochrane Review Groups’ Specialized Registers, the handsearch results register, relevant records retrieved from MEDLINE, and relevant records retrieved from EMBASE, are merged as described here and published as CENTRAL.
The Publishers, John Wiley & Sons Ltd acknowledges the contribution made by Elsevier to CENTRAL by the provision of EMBASE records (Copyright © 2008 Elsevier B.V., Amsterdam. All Rights Reserved). EMBASE records can be identified by a sole EMBASE ID in the Accession Number field. Wiley also thanks Update Software for the continued use of their data formats in CENTRAL.
The Cochrane Methodology Register (CMR)* is a bibliography of publications that report on methods used in the conduct of controlled trials. It includes journal articles, books, and conference proceedings, and the content is sourced from MEDLINE and hand searches. CMR contains studies of methods used in reviews and more general methodological studies that could be relevant to anyone preparing systematic reviews. CMR records contain the title of the article, information on where it was published (bibliographic details), and, in some cases, a summary of the article. They do not contain the full text of the article.
The CMR was produced by the UK Cochrane Centre, until 31st May 2012. The future of the CMR is now currently under review and is not receiving updates. The last Issue with updated was in July 2012. For further information on the status of the CMR please contact Jackie Chandler (Methods co-ordinator) jchandler@cochrane.org.
Further information on using CMR can be viewed here.
The Publishers, John Wiley & Sons Ltd, thanks Update Software for the continued use of their data formats in the Cochrane Methodology Register (CMR).
*Under review, last update incorporated into the July issue
The Health Technology Assessment (HTA) Database brings together details of completed and ongoing health technology assessments (studies of the medical, social, ethical, and economic implications of healthcare interventions) from around the world. The aim of the HTA Database is to improve the quality and cost-effectiveness of health care.
The HTA database is produced by the Centre for Reviews and Dissemination (CRD) at the University of York, UK, using information obtained from members of International Network of Agencies for Health Technology Assessment (INAHTA) and other health technology assessment organizations.
As healthcare resources are finite, information about both costs and effects are essential to making evidence-based decisions about competing healthcare interventions. But information about cost-effectiveness can be difficult to identify, appraise and interpret.
The NHS Economic Evaluation Database (EED) assists decision-makers by systematically identifying economic evaluations from around the world, appraising their quality, and highlighting their relative strengths and weaknesses.
NHS EED is produced by the Centre for Reviews and Dissemination (CRD) at the University of York, UK.
The About The Cochrane Collaboration database contains information on the 81 groups (Issue 4, 2013) that make up The Cochrane Collaboration.
You will find contacts and information on the aims and scope of the Cochrane Review Groups, Methods Groups, Fields, and Networks, along with details of your nearest Cochrane Centre as well as the Cochrane Editorial Unit and the Cochrane Operational Unit.
The Publishers, John Wiley & Sons Ltd, thanks Update Software for the continued use of their data formats for other Cochrane groups (other than Cochrane Review Groups) in this database.
| Database | Year Of Earliest Record | Total published |
|---|---|---|
| Cochrane Database of Systematic Reviews* | 2005 | 7825 |
| Database of Abstracts of Reviews of Effects | 1994 | 22619 |
| Cochrane Central Register of Controlled Trials | 1898 | 692036 |
| Cochrane Methodology Register | 1951 | 15764` |
| Health Technology Assessment Database | 1989 | 12049`` |
| NHS Economic Evaluation Database | 1968 | 13913 |
| About The Cochrane Collaboration** | 2004 | 81 |
| Editorials | 2010 | 56 |
* Comprises 5484 full reviews and 2341 protocols. The April Issue4 2013, contained 35 new reviews, 43 updated reviews (with 9 changed conclusions), 45 new protocols, and 8 updated protocols. Two reviews and 8 protocols were withdrawn in this issue, totalling 201 withdrawn reviews.
** The Cochrane Collaboration: 1; Cochrane Editorial Unit: 1; Cochrane Review Groups (CRGs): 53; Fields: 12; Methods Groups: 16. There are also 14 Centres (some with specific Branches). Links to their individual websites can be found here.
` The CMR database is currently not being updated as from the 31st May due to lack of funding for core activity. It is no longer supported by the UKCC. The plan is to draw together interested individuals to review the current format and focus of this database and consider options to take it forward. If this is of particular interest please contact Jackie chandler jchandler@cochrane.org
``The CRD has advised us that due to a technical error they have been unable to supply the complete database to us for publication. This data will be update in the next issue.
Cochrane database of systematic reviews: in 2012 -2013
| Published Articles | Iss 2 | Iss 3 | Iss 4 | Iss 5 | Iss 6 | Iss 7 | Iss 8 | Iss 9 | Iss 10 | Iss 11 | Iss 12 | Iss 1 | Iss 2 | Iss 3 | Iss 4 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| New reviews | 49 | 32 | 34 | 29 | 28 | 29 | 37 | 54 | 36 | 44 | 50 | 30 | 36 | 31 | 35 |
| Updated reviews | 43 | 35 | 40 | 43 | 48 | 29 | 40 | 56 | 41 | 41 | 68 | 40 | 53 | 42 | 43 |
| New search | 40 | 28 | 32 | 31 | 39 | 25 | 32 | 44 | 36 | 33 | 50 | 33 | 38 | 34 | 34 |
| Conclusions changed | 3 | 7 | 8 | 12 | 9* | 4 | 8 | 12 | 5 | 8 | 18 | 7 | 15 | 8 | 9 |
| New protocols | 67 | 74 | 66 | 59 | 42 | 68 | 44 | 70 | 48 | 72 | 39 | 47 | 77 | 46 | 45 |
| Updated protocols | 11 | 0 | 12 | 15 | 3 | 10 | 12 | 9 | 5 | 2 | 0 | 0 | 17 | 9 | 8 |
| Withdrawn reviews | 3 | 3 | 2 | 2 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 5 | 2 |
| Withdrawn protocols | 5 | 4 | 14 | 20 | 4 | 5 | 4 | 5 | 6 | 6 | 1 | 8 | 4 | 8 | 12 |
| Total in CDSR | 7092 | 7163 | 7227 | 7272 | 7296 | 7366 | 7404 | 7481 | 7530 | 7590 | 7626 | 7637 | 7773 | 7819 | 7825 |
*Amended to include a Change of Conclusion review, without a new search, following feedback/ comment.
Review Title |
Authors |
First Published |
Waters E, de Silva-Sanigorski A, Hall BJ, Brown T, Campbell KJ, Gao Y, Armstrong R, Prosser L, Summerbell CD |
Issue 1, 2001 |
|
|
Statins for the primary prevention of cardiovascular disease. |
Taylor F, Ward K, Moore THM, Burke M, Davey Smith G, Casas JP, Ebrahim S |
Issue 1, 2011 |
|
Interventions for preventing falls in older people living in the community. |
Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG, Rowe BH |
Issue 2, 2009 |
Oude Luttikhuis H, Baur L, Jansen H, Shrewsbury VA, O'Malley C, Stolk RP, Summerbell CD |
Issue 3, 2003 |
|
Singh M, Das RR |
Issue 2, 1999 |
|
McInnes E, Jammali-Blasi A, Bell-Syer SEM, Dumville JC, Cullum N |
Issue 2, 2000 |
|
|
Interventions for preventing falls in older people in nursing care facilities and hospitals. |
Cameron ID, Murray GR, Gillespie LD, Robertson MC, Hill KD, Cumming RG, Kerse N |
Issue 1, 2010 |
Gillespie LD, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH |
Issue 4, 1997 |
|
|
Interventions to improve hand hygiene compliance in patient care. |
Gould DJ, Moralejo D, Drey N, Chudleigh JH |
Issue 2, 2007 |
Shepperd S, McClaran J, Phillips CO, Lannin NA, Clemson LM, McCluskey A, Cameron ID, Barras SL |
Issue 4, 2000 |
|
|
Adverse effects of biologics: a network meta-analysis and Cochrane overview. |
Singh JA, Wells GA, Christensen R, Tanjong Ghogomu E, Maxwell L, MacDonald JK, Filippini G, Skoetz N, Francis DK, Lopes LC, Guyatt GH, Schmitt J, La Mantia L, Weberschock T, Roos JF, Siebert H, Hershan S, Cameron C, Lunn MPT, Tugwell P, Buchbinder R |
Issue 2, 2011 |
Gøtzsche PC, Nielsen M |
Issue 4, 2001 |
|
Zwarenstein M, Goldman J, Reeves S |
Issue 2, 1997 |
|
Haynes RB, Ackloo E, Sahota N, McDonald HP, Yao X |
Issue 3, 1999 |
|
|
Early skin-to-skin contact for mothers and their healthy newborn infants. |
Moore ER, Anderson GC, Bergman N, Dowswell T |
Issue 2, 2003 |
Rimer J, Dwan K, Lawlor DA, Greig CA, McMurdo M, Morley W, Mead GE |
Issue 1, 2004 |
|
Katalinic OM, Harvey LA, Herbert RD, Moseley AM, Lannin NA, Schurr K |
Issue 9, 2010 |
|
|
Midwife-led versus other models of care for childbearing women. |
Hatem M, Sandall J, Devane D, Soltani H, Gates S |
Issue 4, 2008 |
|
Colloids versus crystalloids for fluid resuscitation in critically ill patients. |
Perel P, Roberts I |
Issue 4, 1997 |
Howe TE, Rochester L, Neil F, Skelton DA, Ballinger C |
Issue 4, 2007 |